单倍群O-M122

单倍群O-M122
起源时间	约3万年前[1]
起源地	印度东北部[2]
上游单倍群	单倍群O-M175
下游单倍群	单倍群O-M324（O2a）、单倍群O-F742（O2b）
对应突变	M122[3], CTS10736, CTS10753, F36, F400, F433, F471, F633, P198

单倍群O-M122（英語：）是人类Y染色体DNA单倍群之一，现称O2（旧称O3），是单倍群O-M175的下游单倍群之一。

起源与分布

单倍群O-M122于2万5千年至3万年前首次出现于東亞南部。[1]该单倍群目前主要分佈於东亚、玻里尼西亞、东南亞、中亚、南亚等。O-M122的主要下游单倍群包括（以下均采用ISOGG 2017版命名）:O2a2a-M188、O2a1b-IMS-JST002611、O2a2b1a1-M117、O2a2b1a2-F114、O2a2b2-AM01822、O2b-F742等。其中O2a2a-M188主要分佈在中國南方，在日本、韩國以及、东南亚等地也有分布，其下游的O2a2a1a2-M7主要分佈在苗瑶语族各族，O2a1b-IMS-JST002611、O2a2b1a1-M117、O2a2b1a2-F114是汉族主要的单倍群，也常见于如朝鮮族、滿族、赫哲族、锡伯族、中国蒙古族、土族等中國境内的民族，M117也常见于藏缅语族各族中，F114还在哈萨克族乃蛮部中高频分布。O2a2b2-AM01822主要分佈在中國華北偏東部地區等地，其下游的O2a2b2a2b-AM01847是波利尼西亚人的主要單倍群。O2b-F742主要分佈於中國東部沿海省份等地。

在人群中的比重

族群	比例	樣本數	資料來源	SNPs
独龙族	1		Shi 2009
那加人 (Sagaing, 緬甸)	1.000	15		Page23=15
尼釋人(印度東北	0.94		Cordaux 2004
阿迪人(印度東北)	0.89		Cordaux 2004
塔芒族(尼泊爾)	0.867	45	Gayden 2007	M134
怒族(雲南)	0.86		Wen 2004
瑤族 (連南瑤族自治縣)	0.829	35	Xue 2006	M7=18 M117=5 M122(xM159, M7, M134)=4 M134(xM117)=2
阿昌族(雲南緬甸)	0.825		Shi 2009
阿帕塔尼部落 - Yoair	0.82		Cordaux 2004
白族(雲南)	0.82		Shi 2009
南方漢族 (湖南福建漢族)	0.788	52	Poznik 2016	M122=41
那加人 (東北印度)	0.765	34	Cordaux 2004	M134=26
佤族 (雲南)	0.759	29	Cai 2011	M122
漢族	0.74		Wen 2004
畬族	0.735	34	Xue 2006	M7=10 M122(xM159, M7, M134)=7 M117=6 M134(xM117)=2
怒族	0.7		Shi 2009
苗族	0.7		Karafet 2001
水族	0.7		Shi 2009
漢族 (哈爾濱)	0.657	35	Xue 2006	M122(xM159, M7, M134)=10 M134(xM117)=8 M117=5
傈僳族	0.65		Wen 2004
藻敏方言 (廣東瑤族)	0.649	37	Cai 2011	M122
畬族	0.63		Karafet 2001
菲律賓人	0.62		Jin 2009
台灣漢族	0.619	21	Tajima 2004	M122
菲律賓人	0.607	28	Hurles 2005	M122
漢族 (華東)	0.593	167	Yan 2011	M122
加羅人	0.59		Reddy 2007
越南京族 (越南河內)	0.58	48		M122=28
欽族 (欽邦, 緬甸)	0.579	19		Page23=10 M122(xM324)=1
漢族 (華北)	0.566	129	Yan 2011	M122
多巴巴塔克族 (印尼蘇門答臘)	0.553	38	Karafet 2010	P201(xM7, M134)
北方漢族	0.551	49	Tajima 2004	M122
加羅人	0.55		Kumar 2007
土家族	0.54		Shi 2009
土家族	0.53		Karafet 2001
漢族 (成都)	0.529	34	Xue 2006	M122(xM159, M7, M134)=8 M134(xM117)=5 M117=5
漢族 (東北)	0.524	42	Katoh 2005	M122=22
漢族 (梅县)	0.514	35	Xue 2006	M122(xM159, M7, M134)=10 M117=4 M7=2 M159=1 M134(xM117)=1
北京漢族	0.500	46	Poznik 2016	F444=8 M117=7 JST002611=5 KL2(xJST002611)=2 M188(xM7)=1
漢族 (華南)	0.492	65	Yan 2011	M122
佤族	0.48		Shi 2009
白族	0.48		Shi 2009 Wen 2004
河內京族	0.478	46	Poznik 2016	M7=6 M133=4 F444=4 JST002611=4 KL2(xJST002611)=2 N6>F4124=1 CTS1754=1
韓國人	0.472	216	Kim 2007
傈僳族	0.47		Shi 2009
哈尼族	0.47		Wen 2004
漢族 (伊犁哈薩克自治州)	0.469	32	Xue 2006	M122(xM159, M7, M134)=10 M7=2 M117=2 M134(xM117)=1
白族 (雲南大理)	0.46	50	Wen 2004	M122
蒙古族 (內蒙古包頭市)	0.455	33		F273=2 F4249=2 FGC23868=1 Z26109=1 F133=1 F12=1 Y26383=1 CTS201=1 F8=1 Y20928=1 F748=1 SK1783=1 SK1775=1
Hezhe (China)	0.444	45	Xue 2006	M122(xM159, M7, M134)=11 M134(xM117)=2 M117=7
韓國人	0.443	506	Kim 2011	P201=146 M324(xP201)=76 M122(xM324)=2
藏族 (雲南香格里拉縣)	0.440	50	Wen 2004	M122
苗族	0.44		Shi 2009
彝族	0.44		Wen 2004
拉祜族	0.43		Shi 2009
Bit (Laos)	0.429	28	Cai 2011	M122
滿族 (東北)	0.426	101	Katoh 2005	M122=43
韓民族 (首爾)	0.422	573	Park 2012	M122
韓民族 (大德區)	0.414	133	Park 2012	M122
Hmong Daw (寮國)	0.412	51	Cai 2011	M122
越南人	0.41		Karafet 2001
傣族	0.4		Yang 2005
東干族 (吉爾吉斯)	0.40	40	Wells 2001	M122
藏族	0.400	35	Xue 2006	M117=13 M134(xM117)=1
中國朝鮮族	0.400	25	Xue 2006	M122(xM159, M7, M134)=6 M117=4
撣族 (泰國北部)	0.400	20	Brunelli 2017	M117=7 M7=1
中部泰族	0.395	129	Kutanan 2019	F8/F42*=17 M7=11 JST002611=10 F474/F317=4 F323/F46=4 M159=2 F2055/CTS445=1 F2137=1 F837=1
韓民族 (南韓)	0.395	43	Xue 2006	M122(xM159, M7, M134)=7 M134(xM117)=5 M117=5
越南人	0.39		Jin 2009
北部泰族	0.390	205	Brunelli 2017	O-M117=46 O-M7=17 O-M324(xM7, M134)=16 O-M122(xM324)=1
孟族 (泰國北部)	0.389	18	Brunelli 2017	M117=4 M324(xM7, M134)=3
布朗族 (雲南)	0.385	52	Cai 2011	M122
北部泰族 (Khon Mueang & Tai Yuan)	0.384	86	Kutanan 2019	F8/F42=24 M7=7 JST002611=1 F999/F717=1
滿族	0.38		Karafet 2001
菲律賓人 (他加祿)	0.380	50	Tajima 2004	M122
越南哈尼族	0.375	24	Trejaut 2014	M7=3 M134(xM133)=3 M133=1 JST002611=1 M159=1
Manchu	0.371	35	Xue 2006	M122(xM159, M7, M134)=6 M117=5 M134(xM117)=2
漢族 (蘭州)	0.367	30	Xue 2006	M122(xM159, M7, M134)=6 M117=3 M134(xM117)=2
拉祜族	0.36		Wen 2004
羌族	0.364	33	Xue 2006	M134(xM117)=4 M117=3 M122(xM159, M7, M134)=3 M7=2
緬族 (緬甸)	0.361	72		Page23=26
印尼婆羅洲	0.360	86	Karafet 2010	M122
韓民族	0.356	45	Wells 2001	M122
巴哼語 (廣西瑤族)	0.355	31	Cai 2011	M122
菲律賓人	0.354	48	Karafet 2010	M122
西部裕固語(甘肅突厥)	0.35		Zhou 2008
泰族 (清邁 & 坤敬府)	0.353	34	Shi 2009 Tajima 2004	M122
傣允族 (泰國北部)	0.346	26	Brunelli 2017	M324(xM7, M134)=4 M117=3 M7=2
Tharu	0.345	171	Fornarino 2009	M134
越南京族 (河內)	0.342	76	He 2012	M122
韓民族 (首爾)	0.341	85	Katoh 2005	M122=29
藏族	0.340	156	Gayden 2007	M122
瑤族 (巴馬瑤族自治縣)	0.343	35	Xue 2006	M7=12
哈薩克族 (SE Altai)	0.337	89	Dulik 2011	M134(xM117, P101)
泰沅 (泰國)	0.329	85	Brunelli 2017	M117=15 M7=5 M122(xM324)=5 M134(xM117)=3
傣族 (雲南西雙版納傣族自治州)	0.327	52	Poznik 2016	O-M133=13 O-M7=2 O-F444=1 O-JST002611=1
波利尼西亞人	0.325		Su 2000
藏族	0.32		Wen 2004
Khasi	0.32		Reddy 2007
寮族 (寮國龍坡邦)	0.32	25	He 2012	M122
Eastern Yugur	0.31		Zhou 2008
馬來族	0.31		Karafet 2001
布依族	0.314	35	Xue 2006	M7=6 M134(xM117)=3 M117=1 M122(xM159, M7, M134)=1
喀爾喀蒙古族	0.311		Kim 2011
菲律賓人	0.308	146	Trejaut 2014	P164(xM134)=26 JST002611=7 M7=3 M133=3 M134(xM133)=2 P201(xM159, M7, P164)=2 M159=1 M324(xKL1, P201)=1
漢族 (平話)	0.3		Gan 2008
撒拉族	0.302	43	Wang 2003	M122
侗族	0.300	20	Xie 2004	M134=3 M122(xM7, M134)=3
泰國	0.293	75	Trejaut 2014	M133(xM162)=10 M7=5 M134(xM133)=3 JST002611=2 P164(xM134)=1 M122(xM324)=1
中國朝鮮族	0.291	79	Katoh 2005	M122=23
卡西族	0.29		Kumar 2007
壯族	0.29		Su 2000
內蒙古	0.289	45	Xue 2006	M122(xM159, M7, M134)=5 M117=5 M134(xM117)=3
傣仂族 (泰國北部)	0.286	91	Brunelli 2017	O-M117=16 O-M7=6 O-M324(xM7, M134)=3 O-M122(xM324)=1
壯族	0.286	28	Xie 2004	M134=7 M122(xM7, M134)=1
寮族 (Vientiane & Luang Prabang)	0.275	40	Kutanan 2019	F8/F42=6 M7=2 M188(xM7)=2 P164_{(xF8,F46,F4110,F706,F717)}=1
保安族	0.273	44	Wang 2003	M122
錫伯族	0.268	41	Xue 2006	M134(xM117)=5 M122(xM159, M7, M134)=4 M117=2
密克羅尼西亞(大洋洲)	0.27		Su 2000
孟族 (泰國)	0.267	105	Kutanan 2019	F8/F42=15 M7=4 F323/F46=4 JST002611=3 F2859=1 M122_{(x002611,M188,P164,F837)}=1
达斡尔族	0.256	39	Xue 2006	M122(xM159, M7, M134)=7 M117=3
玻里尼西亞	0.25		Hammer 2005 Kayser 2006
Bunu (Guangxi)	0.25	36	Cai 2011	M122
馬來族 (鄰近吉隆坡)	0.25	12	Tajima 2004	M122
壯族 (廣西)	0.247	166	Chen 2006	M122(xM121, M134)=23 M117=9 M134(xM117)=7 M121=2
日本族 (Kyūshū)	0.240	104	Tajima 2004	M122
東鄉族	0.24		Wang 2003
Manchurian Evenks	0.24		Karafet 2001
Thai (Northern Thailand)	0.235	17	He 2012	M122
Japanese (Kagawa)	0.234	47	Xue 2006	M117=8 M134(xM117)=2 M122(xM159, M7, M134)=1
Mosuo (Ninglang, Yunnan)	0.234	47	Wen 2004	M122
Evenks (China)	0.231	26	Xue 2006	M117=4 M134(xM117)=1 M122(xM159, M7, M134)=1
Mongolia (mainly Khalkhs[4])	0.228	149	Hammer 2005	M134=24 M122(xM134)=10
Zhuang (Napo County, Guangxi)	0.222	63		M117=5 M122(xM188, M134)=4 M188=3 M134(xM117)=2
Lawa (Northern Thailand)	0.220	50	Brunelli 2017	M324(xM7, M134)=6 M117=5
Mal (Laos)	0.220	50	Cai 2011	M122
Cambodian (Siem Reap)	0.216	125	Black 2006	M122
Japanese (Tokushima)	0.214	70	Hammer 2005	M134=11 M122(xM134, LINE)=2 LINE=2
Newar	0.212	66	Gayden 2007	M117
Lao Isan	0.210	62	Kutanan 2019	M7=6 F8=4 JST002611=3
Blang	0.21		Shi 2009
Okinawans	0.21		Nonaka 2007
Tai Khün (Northern Thailand)	0.208	24	Brunelli 2017	M117=4 M134(xM117)=1
Kathmandu, Nepal	0.208	77	Gayden 2007	M324
Sui	0.200	50	Xie 2004	M134=10
Yi (Shuangbai, Yunnan)	0.20	50	Wen 2004	M122(xM7)
Japanese (Shizuoka)	0.197	61	Hammer 2005	M122(xM134, LINE)=7 M134=5
Khmu (Laos)	0.196	51	Cai 2011	M122
Dongxiang	0.196	46	Wang 2003	M122
Oroqen	0.194	31	Xue 2006	M122(xM159, M7, M134)=2 M7=2 M134(xM117)=1 M117=1
Khalkh (Mongolia)	0.188	85	Katoh 2005	M122=16
Japanese (Miyazaki)	0.183	1285	Nohara 2021	M134=118 M122(xM134)=117
Japanese (Tokyo)	0.179	56	Poznik 2016	M117=5 M134(xM117)=3 JST002611=2
Hani	0.176	34	Xue 2006	M134(xM117)=3 M117=2 M122(xM159, M7, M134)=1
Micronesia	0.176	17	Hammer 2005	M122(xM134, LINE)=3
Hui	0.171	35	Xue 2006	M122(xM159, M7, M134)=4 M134(xM117)=1 M117=1
Kalmyk (Khoshuud)	0.171	82	Malyarchuk 2013	M122=14
Japanese	0.167	263	Nonaka 2007	M122
Mandar (Sulawesi)	0.167	54	Karafet 2010	M122
Mulam (Luocheng)	0.167	42	Wang 2003	JST002611=3 M134(xM117)=3 M117=1
Japanese (Kantō)	0.162	117	Katoh 2005	M122=19
Thai	0.16		Jin 2009
Zhuang	0.16		Karafet 2001
Aheu (Laos)	0.158	38	Cai 2011	M122
Bugan (Yunnan)	0.156	32	Cai 2011	M122
Okinawans	0.156	45	Hammer 2005	M122(xM134, LINE)=3 LINE=3 M134=1
Uygur (Yili)	0.154	39	Xue 2006	M122(xM159, M7, M134)=2 M134(xM117)=2 M117=2
Japanese (Aomori)	0.154	26	Hammer 2005	M134=3 M122(xM134, LINE)=1
Cambodia	0.14		Shi 2009
Cham (Binh Thuan, Vietnam)	0.136	59	He 2012	M122
Java (mainly sampled in Dieng)	0.131	61	Karafet 2010	M122
Aboriginal Taiwanese	0.126	223	Tajima 2004	M122
Uighur (Kazakhstan)	0.122	41	Wells 2001	M122
Uzbek (Bukhara)	0.121	58	Wells 2001	M122
Ulchi	0.115	52		O-M122(xP201)=6
Karakalpak (Uzbekistan)	0.114	44	Wells 2001	M122
Utsat (Sanya, Hainan)	0.111	72	Li 2013	M117=3 M122(xM159, M117)=3 M159=2
Outer Mongolian	0.108	65	Xue 2006	M122(xM159, M7, M134)=3 M117=3 M134(xM117)=1
Bo (Laos)	0.107	28	Cai 2011	M122
Tibetans	0.1		Zhou 2008
Maluku Islands	0.1	30	Karafet 2010	M122
Kazakh (Kazakhstan)	0.093	54	Wells 2001	M122
Bouyei	0.089	45	Xie 2004	M122(xM7, M134)=2 M7=1 M134=1
Pumi (Ninglang, Yunnan)	0.085	47	Wen 2004	M122(xM7)
Zakhchin (Mongolia)	0.083	60	Katoh 2005	M122=5
Mongols	0.083	24	Wells 2001	M122
Balinese (Bali)	0.073	641	Karafet 2010	M122
Japanese	0.068	59	Ochiai 2016	P198
Uriankhai (Mongolia)	0.067	60	Katoh 2005	M122=4
Sinte (Uzbekistan)	0.067	15	Wells 2001	M122
Uygur (Urumqi)	0.065	31	Xue 2006	M134(xM117)=1 M117=1
Iranian (Esfahan)	0.063	16	Wells 2001	M122
Kalmyk (Dörwöd)	0.061	165	Malyarchuk 2013	M122=10
Flores	0.046	394	Karafet 2010	M122
Buryat	0.040	298	Kharkov 2014	M324(xM134)=5 M134(xM117)=4 M117=3
Buyei	0.04		Yang 2005
Kalmyk (Torguud)	0.033	150	Malyarchuk 2013	M122=5
Kazakhs (SW Altai)	0.033	30	Dulik 2011	M134(xM117, P101)
Munda (Jharkhand)	0.032	94		M134=3
Burusho	0.031	97	Firasat 2007	M122
Li	0.029	34	Xue 2006	M134(xM117)=1
Sumba	0.029	350	Karafet 2010	M122
Khoton (Mongolia)	0.025	40	Katoh 2005	M122=1
Naxi (Lijiang, Yunnan)	0.025	40	Wen 2004	M134
Rajbanshi (West Bengal)	0.022	45		M134=1
Pathan	0.010	96	Firasat 2007	M122
Pakistan	0.005	638	Firasat 2007	M122

注释

（Shi 2009）
（GenographicProject 2005）
（Krahn and FTDNA 2013）
Karafet, T. M.; Zegura, S. L.; Posukh, O.; Osipova, L.; Bergen, A.; Long, J.; Goldman, D.; Klitz, W.; Harihara, S.; de Knijff, P.; Wiebe, V.; Griffiths, R. C.; Templeton, A. R.; Hammer, M. F. . American Journal of Human Genetics. 1999, 64 (3): 817–831. PMC 1377800 . PMID 10053017. doi:10.1086/302282.

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[#1-1] （Shi 2009）

[2] （GenographicProject 2005）

[3] （Krahn and FTDNA 2013）

[Karafet1999-4] Karafet, T. M.; Zegura, S. L.; Posukh, O.; Osipova, L.; Bergen, A.; Long, J.; Goldman, D.; Klitz, W.; Harihara, S.; de Knijff, P.; Wiebe, V.; Griffiths, R. C.; Templeton, A. R.; Hammer, M. F. . American Journal of Human Genetics. 1999, 64 (3): 817–831. PMC 1377800 . PMID 10053017. doi:10.1086/302282.