烯醇化酶
烯醇化酶(英語:,又被称为磷酸烯醇式丙酮酸水合酶,)是负责催化糖酵解的第九步反应,2-磷酸甘油酸(2-PG)转化为磷酸烯醇式丙酮酸(PEP)的金属酶。其催化的化学反应式为:
- 2-磷酸-D-甘油酸 磷酸烯醇式丙酮酸 + H2O
| phosphopyruvate hydratase | |||||||
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| Yeast enolase dimer.[1] | |||||||
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| 识别码 | |||||||
| EC編號 | 4.2.1.11 | ||||||
| CAS号 | 9014-08-8 | ||||||
| 数据库 | |||||||
| IntEnz | IntEnz浏览 | ||||||
| BRENDA | BRENDA入口 | ||||||
| ExPASy | NiceZyme浏览 | ||||||
| KEGG | KEGG入口 | ||||||
| MetaCyc | 代谢路径 | ||||||
| PRIAM | 概述 | ||||||
| PDB | RCSB PDB PDBj PDBe PDBsum | ||||||
| 基因本体 | AmiGO / EGO | ||||||
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| Enolase, N-terminal domain | |||||||||
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![]() x-ray structure and catalytic mechanism of lobster enolase | |||||||||
| 鑑定 | |||||||||
| 標誌 | Enolase_N | ||||||||
| Pfam | PF03952(旧版) | ||||||||
| Pfam宗系 | CL0227(旧版) | ||||||||
| InterPro | IPR020811 | ||||||||
| PROSITE | PDOC00148 | ||||||||
| SCOP | 1els / SUPFAM | ||||||||
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| Enolase | |||||||||||
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| 鑑定 | |||||||||||
| 標誌 | Enolase | ||||||||||
| Pfam | PF00113(旧版) | ||||||||||
| InterPro | IPR000941 | ||||||||||
| PROSITE | PDOC00148 | ||||||||||
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烯醇化酶裂合酶家族中的水裂解酶类,用于裂解碳氧键。
参考文献
- PDB 2ONE; Zhang E, Brewer JM, Minor W, Carreira LA, Lebioda L. . Biochemistry. October 1997, 36 (41): 12526–34. PMID 9376357. doi:10.1021/bi9712450.
- PDB 2XSX; Vollmar M, Krysztofinska E, Chaikuad A, Krojer T, Cocking R, Vondelft F, Bountra C, Arrowsmith CH, Weigelt J, Edwards A, Yue WW, Oppermann U. . To be published. 2010.
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