夫西地酸

**夫西地酸**
臨床資料
商品名	Fucidin, Fucithalmic, Stafine
其他名稱	Sodium fusidate
AHFS/Drugs.com	Micromedex详细消费者药物信息
ATC碼	D06AX01 (WHO) D09AA02 (dressing) J01XC01 S01AA13;
藥物動力學數據
生物利用度	91% oral bioavailability
血漿蛋白結合率	97 to 99%
生物半衰期	Approximately 5 to 6 hours in adults
识别
	IUPAC命名法 2-[(1S,2S,5R,6S,7S,10S,11S,13S,14Z,15R,17R)-13-(acetyloxy)-5,17-dihydroxy-2,6,10,11-tetramethyltetracyclo[8.7.0.02,7.011,15]heptadecan-14-ylidene]-6-methylhept-5-enoic acid; ;
CAS号	6990-06-3
PubChem CID	3000226;
DrugBank	DB02703 ;
ChemSpider	2271900 ;
UNII	59XE10C19C;
KEGG	D04281 ;
ChEBI	CHEBI:29013 ;
ChEMBL	ChEMBL374975 ;
PDB配體ID	FUA (PDBe, RCSB PDB);
CompTox Dashboard (EPA)	DTXSID0023086 ;
ECHA InfoCard	100.027.506
化学
化学式	C31H48O6
摩尔质量	516.709
3D模型（JSmol）	交互式图像;
	SMILES O=C(O)/C(=C3/[C@@H]2C[C@@H](O)[C@H]1[C@@]4(C)CC[C@@H](O)[C@@H](C)[C@@H]4CC[C@@]1([C@]2(C[C@@H]3OC(=O)C)C)C)CC\C=C(/C)C;
	InChI InChI=1S/C31H48O6/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36)/b26-20-/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-/m0/s1 ; Key:IECPWNUMDGFDKC-MZJAQBGESA-N ;

夫西地酸（英語：）是一种甾类抗生素，通常局部用于面霜和眼药水，也可作为片剂或注射剂全身使用。在全球范围内，细菌抗生素抗藥性的提高引起了人们对其使用的新兴趣[1]。

参考文献

Falagas ME, Grammatikos AP, Michalopoulos A. Potential of old-generation antibiotics to address current need for new antibiotics. Expert Rev Anti Infect Ther. 2008; 6(5):593-600 doi:10.1586/14787210.6.5.593 PMID 18847400

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