PD-128,907

PD-128,907（3,4,4a,10b-四氢-4-丙基-2H,5H-[1]苯并吡喃并[4,3-b]-1,4-噁嗪-9-酚），分子式C14H19NO3，是一种用于科研的多巴胺受體D2和D3激动剂[1]。其合成已有文献报道。[2]

PD-128,907
识别
  • (4aR,10bR)-3,4a,4,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano-[4,3-b]-1,4-oxazin-9-ol
CAS号123594-64-9  checkY
300576-59-4（盐酸盐）
PubChem CID
ChemSpider
ChEMBL
化学
化学式C14H19NO3
摩尔质量249.31 g·mol−1
3D模型（JSmol）
  • c23cc(O)ccc3OCC1C2OCCN1CCC
  • InChI=1S/C14H19NO3/c1-2-5-15-9-17-7-12-11-6-10(16)3-4-14(11)18-8-13(12)15/h3-4,6,12-13,16H,2,5,7-9H2,1H3/t12-,13-/m1/s1 ☒N
  • Key:ZFSOBPVEIKTNQS-CHWSQXEVSA-N ☒N

参考文献
  1. DeWald HA, Heffner TG, Jaen JC, Lustgarten DM, McPhail AT, Meltzer LT, et al. . Journal of Medicinal Chemistry. January 1990, 33 (1): 445–50. PMID 1967318. doi:10.1021/jm00163a068.
  2. Battiti, Francisco O.; Newman, Amy Hauck; Bonifazi, Alessandro. . ACS Medicinal Chemistry Letters (American Chemical Society (ACS)). 2020-02-28, 11 (10): 1956–1964. ISSN 1948-5875. doi:10.1021/acsmedchemlett.9b00660.
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