CYP27C1

CYP27C1
識別號
别名	CYP27C1；, cytochrome P450 family 27 subfamily C member 1
外部ID	HomoloGene：70240 GeneCards：CYP27C1
基因位置（人类）
染色体	2號染色體[1]
终止	127,220,313 bp[1]
基因本體
分子功能	• iron ion binding; • oxidoreductase activity; • heme binding; • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; • 金屬離子結合; • monooxygenase activity; • retinoic acid binding; • 11-cis retinal binding; • all-trans retinal binding; • all-trans-retinol binding; • all-trans retinol 3,4-desaturase activity; • all-trans retinal 3,4-desaturase activity; • all-trans retinoic acid 3,4-desaturase activity; • 11-cis-retinal 3,4-desaturase activity;
細胞組分	• 膜; • 细胞组件; • 細胞內膜結合細胞器;
生物學過程	• retinol metabolic process; • retinoic acid metabolic process; • retinal metabolic process;
	Sources:Amigo / QuickGO
直系同源
	339761
	无数据
	ENSG00000186684
	无数据
	Q4G0S4
	无数据
	NM_001001665; NM_001367501; NM_001367502
	无数据
	NP_001001665; NP_001354430; NP_001354431
	无数据
	維基數據

细胞色素 P450 27C1（英語：，缩写CYP27C1）是细胞色素P450超家族的一员，由CYP27C1基因编码，是定位于许多不同组织线粒体内膜的单加氧酶[3][4]。CYP27C1在体内的主要功能是将视黄醇（维生素A1）转化为维生素A2[5]，此外还能催化多种反应，如胆固醇、甾体激素的合成与代谢[6]。

参考文献

GRCh38: Ensembl release 89: ENSG00000186684 - Ensembl, May 2017
. National Center for Biotechnology Information, U.S. National Library of Medicine.
Ota T, Suzuki Y, Nishikawa T, et al. . Nat. Genet. January 2004, 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285 .
Gerhard DS, Wagner L, Feingold EA, et al. . Genome Res. October 2004, 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Kramlinger, VM; Nagy, LD; Fujiwara, R; Johnson, KM; Phan, TT; Xiao, Y; Enright, JM; Toomey, MB; Corbo, JC; Guengerich, FP. . FEBS letters. 2016-05, 590 (9): 1304–12. PMID 27059013. doi:10.1002/1873-3468.12167.
. （原始内容存档于2010-12-05）.

醫學主題詞表（MeSH）：Cytochrome+P-450+CYP27C1
Human CYP27C1 genome location and CYP27C1 gene details page in the UCSC Genome Browser.

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