CXCL7
趋化因子CXCL7（英語：，CXCL7）是一个人类基因[1]。其编码的蛋白质为趋化因子（C-X-C基序）配体7 ，是一种CXC趋化因子类细胞因子，其蛋白异型体为β-血小板球蛋白或原血小板碱性蛋白（英語：，PPBP）[2]。
| Pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 PDB rendering based on 1f9p. | |||||||||||||
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| 标识 | |||||||||||||
| 代号 | PPBP; B-TG1; Beta-TG; CTAP-III; CTAP3; CTAPIII; CXCL7; LA-PF4; LDGF; MDGF; NAP-2; PBP; SCYB7; TC1; TC2; TGB; TGB1; THBGB; THBGB1 | ||||||||||||
| 扩展标识 | 遗传学：121010 鼠基因：1888712 同源基因：48122 GeneCards: PPBP Gene | ||||||||||||
| RNA表达模式 | |||||||||||||
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| 更多表达数据 | |||||||||||||
| 直系同源体 | |||||||||||||
| 物种 | 人类 | 小鼠 | |||||||||||
| Entrez | 5473 | 57349 | |||||||||||
| Ensembl | ENSG00000163736 | ENSMUSG00000029372 | |||||||||||
| UniProt | P02775 | Q9EQI5 | |||||||||||
| mRNA序列 | NM_002704 | NM_023785 | |||||||||||
| 蛋白序列 | NP_002695 | NP_076274 | |||||||||||
| 基因位置 |
Chr 4: 74.85 – 74.85 Mb |
Chr 5: 90.77 – 90.77 Mb | |||||||||||
| PubMed查询 | |||||||||||||
这种蛋白在血小板活化时被大量释放[3] ，能刺激多种过程，包括有丝分裂、细胞外基质的合成、糖代谢和纤溶酶原激活物的合成[4][5]。
参考文献
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