香柑内酯

**香柑内酯**
臨床資料
给药途径	口服
ATC碼	D05BA03 (WHO) ;
法律規範狀態
法律規範	处方药（℞-only）;
识别
	IUPAC命名法 5-methoxy-2H-furo[3,2-g]chromen-2-one; ;
CAS号	484-20-8
PubChem CID	2355;
ChemSpider	2265 ;
UNII	4FVK84C92X;
KEGG	D07521 ;
ChEMBL	ChEMBL24171 ;
CompTox Dashboard (EPA)	DTXSID1025560 ;
ECHA InfoCard	100.006.913
化学
化学式	C12H8O4
摩尔质量	216.19 g/mol
3D模型（JSmol）	交互式图像;
	SMILES O=C\1Oc3c(/C=C/1)c(OC)c2ccoc2c3;
	InChI InChI=1S/C12H8O4/c1-14-12-7-2-3-11(13)16-10(7)6-9-8(12)4-5-15-9/h2-6H,1H3 ; Key:BGEBZHIAGXMEMV-UHFFFAOYSA-N ;

香柑内酯（5-甲氧补骨脂素）是一种存在于香柠檬精油与其他柑橘属植物精油[1]，以及葡萄柚汁中的呋喃香豆素（furanocoumarin），属补骨脂素的衍生物。[2] 它是香柠檬精油中引起光敏性（光毒性）的活性物质。[3] 目前市面上的香水采用的是不含香柑内酯的香柠檬精油或人工合成的类似香味物质。

医学上香柑内酯与长波紫外线（UVA）一同用于银屑病的長波紫外線光化治療。[4][5]

参考资料

Calvarano I., Calvarano M., Gionfriddo F., Bovalo F., Postorino E. . Essenze Derivati agrumari. 1995, 65: 488–502.
Sakamaki N., Nakazato M., Matsumoto H., Hagino K., Hirata K., Ushiyama H. . Journal of the Food Hygienic Society of Japan. 2008, 49 (4): 326–331. PMID 18787320. doi:10.3358/shokueishi.49.326.
Francesco Gionfriddo, Enrico Postorino and Giuseppe Calabrò. . Perfumer & Flavorist. 2004, 29.
HONIGSMANN, HERBERT; JASCHKE, ERNA; GSCHNAIT, FRITZ; BRENNER, WILHELM; FRITSCH, PETER; WOLFF, KLAUS. . British Journal of Dermatology (Wiley-Blackwell). 1979, 101 (4): 369–378. ISSN 0007-0963. doi:10.1111/j.1365-2133.1979.tb00014.x.
A. Tanew, B. Ortel, K. Rappersberger, H. Hönigsmann. . Journal of the American Academy of Dermatology. 1988-2, 18 (2 Pt 1): 333–338 [2019-05-25]. ISSN 0190-9622. PMID 3279089. 请检查|date=中的日期值 (帮助)

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[1] Calvarano I., Calvarano M., Gionfriddo F., Bovalo F., Postorino E. . Essenze Derivati agrumari. 1995, 65: 488–502.

[2] Sakamaki N., Nakazato M., Matsumoto H., Hagino K., Hirata K., Ushiyama H. . Journal of the Food Hygienic Society of Japan. 2008, 49 (4): 326–331. PMID 18787320. doi:10.3358/shokueishi.49.326.

[3] Francesco Gionfriddo, Enrico Postorino and Giuseppe Calabrò. . Perfumer & Flavorist. 2004, 29.

[4] HONIGSMANN, HERBERT; JASCHKE, ERNA; GSCHNAIT, FRITZ; BRENNER, WILHELM; FRITSCH, PETER; WOLFF, KLAUS. . British Journal of Dermatology (Wiley-Blackwell). 1979, 101 (4): 369–378. ISSN 0007-0963. doi:10.1111/j.1365-2133.1979.tb00014.x.

[5] A. Tanew, B. Ortel, K. Rappersberger, H. Hönigsmann. . Journal of the American Academy of Dermatology. 1988-2, 18 (2 Pt 1): 333–338 [2019-05-25]. ISSN 0190-9622. PMID 3279089. 请检查|date=中的日期值 (帮助)