萘丁美酮

萘丁美酮英語:)是一种有机化合物,分子式C15H16O2,属于非甾体抗炎药(NSAID)[1],1991年由Beecham开发[2]

萘丁美酮
臨床資料
AHFS/Drugs.comMonograph
MedlinePlusa692022
给药途径By mouth
ATC碼
法律規範狀態
法律規範
藥物動力學數據
血漿蛋白結合率> 99% (active metabolite)
药物代谢Liver, to active metabolite 6-methoxy-2-naphthylacetic acid; 6-MNA
生物半衰期23 hours (active metabolite)
排泄途徑Kidney
识别
  • 4-(6-methoxy-2-naphthyl)-2-butanone
CAS号42924-53-8  checkY
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.169.752
化学
化学式C15H16O2
摩尔质量228.29 g·mol−1
3D模型(JSmol
  • O=C(C)CCc1ccc2c(c1)ccc(OC)c2
  • InChI=1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3 checkY
  • Key:BLXXJMDCKKHMKV-UHFFFAOYSA-N checkY

参考文献

  1. Gonzalo-Garijo MA, Cordobés-Duran C, Lamilla-Yerga AM, Moreno-Gastón I. . Journal of Investigational Allergology & Clinical Immunology. 2007, 17 (4): 274–276. PMID 17694703.
  2. . RCSB Protein Data Bank. [5 August 2021]. (原始内容存档于2023-08-06) (美国英语).
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