腺苷再攝取抑制劑

腺苷再攝取抑制劑(Adenosine reuptake inhibitor,縮寫為AdoRI)是一類藥物,它通過阻斷一個或多個平衡核苷轉運蛋白(ENTs)的作用,作為嘌呤核苷神經遞質腺苷再攝取抑制劑[1][2][3]這繼而導致腺苷的細胞外濃度增加,因此腺苷能神經傳遞增加。

參考資料

  1. SenGupta DJ, Unadkat JD. . Biochem Pharmacol. 2004, 67 (3): 453–458. PMID 15037197. doi:10.1016/j.bcp.2003.09.018.
  2. Endres CJ, Sengupta DJ, Unadkat JD. . Biochem J. 2004, 380 (1): 131–137. PMC 1224139可免费查阅. PMID 14759222. doi:10.1042/BJ20031880.
  3. Chaudary N, Naydenova Z, Shuralyova I, Coe IR. . J Pharmacol Exp Ther. 2004, 310 (3): 1190–1198. PMID 15131243. doi:10.1124/jpet.104.067157.
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