己二烯雌酚

己二烯雌酚英語:)是一种非甾体雌激素,是乙烯雌酚衍生物,比己烯雌酚多一个不饱和度,在美国欧盟用作治疗更年期综合征的药物[1][2][3][4]。也有研究将其用作男性前列腺癌直肠给药药物[5]

己二烯雌酚
臨床資料
商品名Ortho Dienestrol, Dienoestrol, Dienoestrol Ortho, Sexadien, Cycladiene, Denestrolin, Dienol, Dinovex, Follormon, Oestrodiene, Synestrol
其他名稱Dienoestrol; p-[(E,E)-1-Ethylidene-2-(p-hydroxyphenyl)-2-butenyl]phenol; 3,4-Di(para-hydroxyphenyl)-2,4-hexadiene
AHFS/Drugs.comMicromedex详细消费者药物信息
藥物類別Nonsteroidal estrogen
ATC碼
识别
  • 4-[4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol
CAS号13029-44-2  ☒N
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard100.001.381
化学
化学式C18H18O2
摩尔质量266.34 g·mol−1
3D模型(JSmol
  • Oc2ccc(C(/C(c1ccc(O)cc1)=C/C)=C\C)cc2
  • InChI=1S/C18H18O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h3-12,19-20H,1-2H3/b17-3+,18-4+ checkY
  • Key:NFDFQCUYFHCNBW-SCGPFSFSSA-N checkY

参考文献

  1. . Taylor & Francis. January 2000: 331–. ISBN 978-3-88763-075-1.
  2. J. Elks. . Springer. 14 November 2014: 390–. ISBN 978-1-4757-2085-3.
  3. Muller. . CRC Press. 19 June 1998: 361–. ISBN 978-3-7692-2114-5.
  4. William Andrew Publishing. . Elsevier. 22 October 2013: 1286–. ISBN 978-0-8155-1856-3.
  5. Sambuelli M. [Rectal administration of estrogens in prostate carcinoma]. Minerva Urol. 1953, 5 (1): 28–32. ISSN 0026-4989. PMID 13063334 (意大利语).
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